When Bitdefender setup for multiple devices, it's crucial to consider a few key factors. Firstly, ensure you have the correct number of licenses to cover all devices. Next, confirm compatibility with each operating system and version. Additionally, establish a centralized Bitdefender account for easy management. Define user permissions and preferences to tailor protection levels. Set up automatic updates to guarantee all devices have the latest definitions. Finally, schedule scans during off-peak times to avoid disruptions.